Crohn's Disease, Ulcerative Colitis & Irritable Bowel
These are autoimmune diseases and there is new testing available to heal your colon and restore your health. It starts with a “leaky gut.” You need to know what foods, chemicals, infections and metals are causing your autoimmune disease.
The gastrointestinal system is the primary gateway by which the external environment interacts with the body. It continuously works to distinguish between beneficial and harmful influences. Even with small aberration in its function, we can have problematic results.
Problems with digestion and absorption may occur mechanically, in functions such as mastication, motility or permeability, and often originate from genetic changes or enzyme changes. Loss of digestion and absorption efficiency may lead to gas, bloating, diarrhea, pain, constipation, all indicating that the system is irritable.
Gut irritability left untreated may lead to leaky gut and development of food allergies, bacterial or yeast overgrowth, and the production of toxins. Toxins may accelerate the irritation and leakiness resulting in toxic molecules entering the portal and systemic circulation. This creates stress on systemic defenses leading to immune, hormonal and inflammatory balances. If the system is left unchecked, and eventually outstrips the body’s adaption, adrenal insufficiency may occur.
SYMPTOMS AND CONDITIONS:
Gastrointestinal disorders to be discussed include celiac disease, Crohn’s, ulcerative colitis, and irritable bowel. There is a complex interaction between enzymatic function which starts in the mouth and continues in the stomach and small intestine, with final elimination through the colon and rectum.
FOOD AS TRIGGERS; ALLERGY AND SENSITIVITY:
The complex mechanism of sorting out nutrients from non-nutrients at the level of the gut mucosa are very complex.
The following is a list of food-illness interactions.
- Asthma- Although most cases are associated with an increase attributed to airborne rather than food allergies, the role of dietary factors has been investigated and several studies link food to asthma. Change in diet, along with fish oils and inhibitation of inflammation has shown improvement. Atopic dermatitis, childhood migraines, gluten, and dairy also have been associated with systemic food insult. The antigliadin antibody and many others are essential. I perform food allergy testing as well as an elimination diet in my office. Several different laboratories are used, using different procedures. I have had them on myself and found them to be very effective. I also to autoantibody and gluten testing
- Inflammation reduction – It is very important to optimize inflammation in the gut. I feel that it is best to have anti-inflammatory foods, herbs, as well as spices. Clearly, essential fatty acids play a role as with glutamine and others. Curcumin, cats claw, green tea, and cruciferous vegetables also lower inflammation.
- Gut permeability – Leaky gut or intestinal hyperpermeability is a common clinical syndrome implicated in a wide array of conditions. Arabinogalactan, large fiber, butyrate and glutamine as well as beneficial flora are effective in treatments.
- Heavy metals – Heavy metal accumulation may also play a part in poor digestion, due to its association with degraded enzyme function, dysbiosis, and bacterial or fungal overgrowth. The primary site of metal poisoning is the level of the metalloenzymes, the site of catalytic function within the enzymes. In the simplest term, the heavy metal displaces the mineral at the metalloenzyme site, resulting in degraded or absent enzyme function. This impedes
digestion and increases leaky gut.
- Gluten and gluten associated foods
- Infections – Viruses, parasites, bacteria, lyme disease
LABORATORY TESTING AND GASTROINTESTINAL DISEASE
It all starts with reliable autoantibody testing. We use a specialized lab which is not available through commercial labs such as Sonora Quest or LabCorp.
- Fat absorption is important to test. If secretions from the pancreas and liver are adequate, absorption of dietary fat is almost complete. To assess for adequacy of digestion absorption of fat, a fecal fat analysis can be done. When the patient has large, greasy, foul-smelling stool, this is called steatorrhea and can cause digestive disorders such as failure of the pancreas and other systems.
- Other testing that I perform evaluates enzyme function, which is needed for digestion.
- Microbiology testing is important to look at pathogens such as abnormal bacteria, fungus and parasites, as well as Bifidobacterium species.
- Measurements of inflammation include eosinophil protein X. EPX is elevated inflammatory bowel disease, and can be useful for evaluating disease activity and predicting relapse. Calprotectin, when elevated, can help distinguish irritable bowel syndrome from inflammatory bowel syndrome, and is also seen in bowel cancer and polyp disease.
- Intestinal permeability is performed using a mannitol lactulose test where leaky gut can be diagnosed.
- Direct visualization is through an esophagogastroduodenoscopy (EGD) or colonoscopy.
As discussed above, this is an autoimmune disease. You need to know which autoantibodies are initiating the destruction of your colonic cells and how to repair your microbiome. The health of your colon can now be measured and restored. We used specialized therapies to get to the root of the problem.